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Whole cell biophysical modeling of codon-tRNA competition reveals novel insights related to translation dynamics

The importance of mRNA translation models has been demonstrated across many fields of science and biotechnology. However, a whole cell model with codon resolution and biophysical dynamics is still lacking. We describe a whole cell model of translation for E. coli. The model simulates all major trans...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Levin, Doron, Tuller, Tamir
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375613/
https://ncbi.nlm.nih.gov/pubmed/32649657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008038
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