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Whole cell biophysical modeling of codon-tRNA competition reveals novel insights related to translation dynamics
The importance of mRNA translation models has been demonstrated across many fields of science and biotechnology. However, a whole cell model with codon resolution and biophysical dynamics is still lacking. We describe a whole cell model of translation for E. coli. The model simulates all major trans...
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| Publié dans: | PLoS Comput Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7375613/ https://ncbi.nlm.nih.gov/pubmed/32649657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008038 |
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