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Inhibitors of metalloprotease, γ-sectretase, protein kinase C and Rho kinase inhibit wild-type adenoviral replication

Adenoviruses cause upper respiratory infections, conjunctivitis, keratitis, and gastrointestinal illness. These can be fatal in immunocompromised individuals. Adenoviruses have also been engineered into viral vectors to deliver therapeutic genes or induce immunity as vaccine carriers. The success of...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Liu, Alice, Ildefonso, Cristhian J., Bond, Wesley S., Hurwitz, Mary Y., Hurwitz, Richard L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375579/
https://ncbi.nlm.nih.gov/pubmed/32697798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236175
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