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Inhibitors of metalloprotease, γ-sectretase, protein kinase C and Rho kinase inhibit wild-type adenoviral replication

Adenoviruses cause upper respiratory infections, conjunctivitis, keratitis, and gastrointestinal illness. These can be fatal in immunocompromised individuals. Adenoviruses have also been engineered into viral vectors to deliver therapeutic genes or induce immunity as vaccine carriers. The success of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Alice, Ildefonso, Cristhian J., Bond, Wesley S., Hurwitz, Mary Y., Hurwitz, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375579/
https://ncbi.nlm.nih.gov/pubmed/32697798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236175
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