An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses

CD137 is a costimulatory receptor expressed on natural killer cells, T cells, and subsets of dendritic cells. An agonistic monoclonal antibody (mAb) against CD137 has been used to reduce tumor burden or reverse autoimmunity in animal models and clinical trials. Here, we show that mice treated with a...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep Med
Asıl Yazarlar: Hong, Jun P., Reynoso, Glennys V., Andhey, Prabhakar S., Swain, Amanda, Turner, Jackson S., Boon, Adrianus C.M., Krammer, Florian, Ellebedy, Ali H., Zanini, Fabio, Artyomov, Maxim, Hickman, Heather D., Diamond, Michael S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375459/
https://ncbi.nlm.nih.gov/pubmed/32699843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100035
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