Insights Into the Mechanism of MCT8 Oligomerization

Mutations in the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) result in MCT8 deficiency, characterized by severe intellectual and motor disability. The MCT8 protein is predicted to have 12 transmembrane domains (TMDs) and is expressed as monomers, homodimers, and homo-oligomers....

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Groeneweg, Stefan, van den Berge, Amanda, Lima de Souza, Elaine C, Meima, Marcel E, Peeters, Robin P, Visser, W Edward
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375341/
https://ncbi.nlm.nih.gov/pubmed/32724870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa080
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