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Discovery of a Novel Hybrid of Vorinostat and Riluzole as a Potent Antitumor Agent
Vorinostat (suberoylanilide hydroxamic acid) was the first approved histone deacetylase (HDAC) inhibitor in a group of validated cancer therapeutic agents targeting epigenetics. Riluzole is a drug used to treat amyotrophic lateral sclerosis, the antitumor potency of which has been recently revealed....
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7375020/ https://ncbi.nlm.nih.gov/pubmed/32760715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00454 |
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