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Blockade of the TLR4–MD2 complex lowers blood pressure and improves vascular function in a murine model of type 1 diabetes

While the pathogenesis of diabetes-induced high blood pressure (BP) is not entirely clear, current evidence suggests that Toll-like receptor 4 (TLR4) is a key player in the mechanisms associated with hypertension. However, it is unknown whether this receptor affects BP under type 1 diabetes. Likewis...

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Publicat a:Sci Rep
Autors principals: de Oliveira, Amanda Almeida, Faustino, Josemar, Webb, R. Clinton, Nunes, Kenia Pedrosa
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374604/
https://ncbi.nlm.nih.gov/pubmed/32694567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68919-x
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