Crosstalk of TLR4, vascular NADPH oxidase, and COVID-19 in diabetes: What are the potential implications?

Toll-like receptor 4 (TLR4) contributes to the pathophysiology of diabetes. This happens, at least in part, because TLR4 modulates the enzyme NADPH oxidase, a primary source of ROS in vascular structures. Increased oxidative stress disrupts key vascular signaling mechanisms and drives the progressio...

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Bibliografiske detaljer
Udgivet i:Vascul Pharmacol
Main Authors: de Oliveira, Amanda Almeida, Nunes, Kenia Pedrosa
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Inc. 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152239/
https://ncbi.nlm.nih.gov/pubmed/34051372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2021.106879
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