Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2

To date, limited genetic changes in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome have been described. Here, we report a 382-nucleotide (nt) deletion in SARS-CoV-2 that truncates open reading frame 7b (ORF7b) and ORF8, removing the ORF8 transcription regulatory sequence (TR...

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Udgivet i:mBio
Main Authors: Su, Yvonne C. F., Anderson, Danielle E., Young, Barnaby E., Linster, Martin, Zhu, Feng, Jayakumar, Jayanthi, Zhuang, Yan, Kalimuddin, Shirin, Low, Jenny G. H., Tan, Chee Wah, Chia, Wan Ni, Mak, Tze Minn, Octavia, Sophie, Chavatte, Jean-Marc, Lee, Raphael T. C., Pada, Surinder, Tan, Seow Yen, Sun, Louisa, Yan, Gabriel Z., Maurer-Stroh, Sebastian, Mendenhall, Ian H., Leo, Yee-Sin, Lye, David Chien, Wang, Lin-Fa, Smith, Gavin J. D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374062/
https://ncbi.nlm.nih.gov/pubmed/32694143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01610-20
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