Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients

Virus-specific humoral and cellular immunity act synergistically to protect the host from viral infection. We interrogate the dynamic changes of virological and immunological parameters in 12 patients with symptomatic acute SARS-CoV-2 infection from disease onset to convalescence or death. We quanti...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Tan, Anthony T., Linster, Martin, Tan, Chee Wah, Le Bert, Nina, Chia, Wan Ni, Kunasegaran, Kamini, Zhuang, Yan, Tham, Christine Y.L., Chia, Adeline, Smith, Gavin J.D., Young, Barnaby, Kalimuddin, Shirin, Low, Jenny G.H., Lye, David, Wang, Lin-Fa, Bertoletti, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: The Author(s). 2021
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826084/
https://ncbi.nlm.nih.gov/pubmed/33516277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108728
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