Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction

Tightly interlinked feedback regulators control the dynamics of intracellular responses elicited by the activation of signal transduction pathways. Interferon alpha (IFNα) orchestrates antiviral responses in hepatocytes, yet mechanisms that define pathway sensitization in response to prestimulation...

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Pubblicato in:Mol Syst Biol
Autori principali: Kok, Frédérique, Rosenblatt, Marcus, Teusel, Melissa, Nizharadze, Tamar, Gonçalves Magalhães, Vladimir, Dächert, Christopher, Maiwald, Tim, Vlasov, Artyom, Wäsch, Marvin, Tyufekchieva, Silvana, Hoffmann, Katrin, Damm, Georg, Seehofer, Daniel, Boettler, Tobias, Binder, Marco, Timmer, Jens, Schilling, Marcel, Klingmüller, Ursula
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373899/
https://ncbi.nlm.nih.gov/pubmed/32696599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20198955
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