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Short-term information processing, long-term responses: Insights by mathematical modeling of signal transduction: Early activation dynamics of key signaling mediators can be predictive for cell fate decisions

How do cells interpret information from their environment and translate it into specific cell fate decisions? We propose that cell fate is already encoded in early signaling events and thus can be predicted from defined signal properties. Specifically, we hypothesize that the time integral of activa...

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Bibliografski detalji
Glavni autori: Schneider, Annette, Klingmüller, Ursula, Schilling, Marcel
Format: Artigo
Jezik:Inglês
Izdano: WILEY-VCH Verlag 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440590/
https://ncbi.nlm.nih.gov/pubmed/22528856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201100172
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