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New insights into the mechanism of dynein motor regulation by lissencephaly-1

Lissencephaly (‘smooth brain’) is a severe brain disease associated with numerous symptoms, including cognitive impairment, and shortened lifespan. The main causative gene of this disease – lissencephaly-1 (LIS1) – has been a focus of intense scrutiny since its first identification almost 30 years a...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Markus, Steven M, Marzo, Matthew G, McKenney, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373426/
https://ncbi.nlm.nih.gov/pubmed/32692650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59737
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