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A Cytoplasmic Dynein Tail Mutation Impairs Motor Processivity
Mutations in the tail of the cytoplasmic dynein molecule have been reported to cause neurodegenerative disease in mice. The mutant mouse strain Legs at Odd Angles (Loa) exhibits impaired retrograde axonal transport, but the molecular deficiencies in the mutant dynein molecule, and how they contribut...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3385513/ https://ncbi.nlm.nih.gov/pubmed/21102439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2127 |
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