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Development and application of in vivo molecular traps reveals that dynein light chain occupancy differentially affects dynein-mediated processes

The ability to rapidly and specifically regulate protein activity combined with in vivo functional assays and/or imaging can provide unique insight into underlying molecular processes. Here we describe the application of chemically induced dimerization of FKBP to create nearly instantaneous high-aff...

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Autori principali: Varma, Dileep, Dawn, Amrita, Ghosh-Roy, Anindya, Weil, Sarah J., Ori-McKenney, Kassandra M., Zhao, Yanqiu, Keen, James, Vallee, Richard B., Williams, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840451/
https://ncbi.nlm.nih.gov/pubmed/20133681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908959107
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