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Neuronal migration defects in the Loa dynein mutant mouse

BACKGROUND: Cytoplasmic dynein and its regulatory proteins have been implicated in neuronal and non-neuronal cell migration. A genetic model for analyzing the role of cytoplasmic dynein specifically in these processes has, however, been lacking. The Loa (Legs at odd angles) mouse with a mutation in...

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Bibliographic Details
Main Authors: Ori-McKenney, Kassandra M, Vallee, Richard B
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127822/
https://ncbi.nlm.nih.gov/pubmed/21612657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-6-26
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