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Structure and function of polycystin channels in primary cilia

Variants in genes which encode for polycystin-1 and polycystin-2 cause most forms of autosomal dominant polycystic disease (ADPKD). Despite our strong understanding of the genetic determinants of ADPKD, we do not understand the structural features which govern the function of polycystins at the mole...

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Bibliografiske detaljer
Udgivet i:Cell Signal
Main Authors: Ta, Chau My, Vien, Thuy N., Ng, Leo C.T., DeCae, Paul G.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373203/
https://ncbi.nlm.nih.gov/pubmed/32251715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2020.109626
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