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Inward Ca(2+) current through the polycystin-2-dependent channels of renal primary cilia

In 15% of cases, autosomal dominant polycystic kidney disease arises from defects in polycystin-2 (PC2). PC2 is a member of the polycystin transient receptor potential subfamily of cation-conducting channels and is expressed in the endoplasmic reticulum and primary cilium of renal epithelial cells....

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Renal Physiol
Hoofdauteurs: Kleene, Steven J., Kleene, Nancy K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285651/
https://ncbi.nlm.nih.gov/pubmed/33969696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00062.2021
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