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Uncovering a Shared Epitope–Activated Protein Citrullination Pathway

Rheumatoid arthritis (RA) is closely associated with shared epitope (SE)–coding HLA-DRB1 alleles and circulating anticitrullinated protein Abs (ACPA), but neither the respective pathogenic roles of SE and ACPA in RA nor the mechanisms underlying their coassociation are known. It was recently shown t...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: van Drongelen, Vincent, Ali, Wahida H., Holoshitz, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372319/
https://ncbi.nlm.nih.gov/pubmed/32591395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901108
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