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Quantitative Interpretation of Solvent Paramagnetic Relaxation for Probing Protein–Cosolute Interactions

Protein–small cosolute molecule interactions are ubiquitous and known to modulate the solubility, stability, and function of many proteins. Characterization of such transient weak interactions at atomic resolution remains challenging. In this work, we develop a simple and practical NMR method for ex...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Okuno, Yusuke, Szabo, Attila, Clore, G. Marius
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372007/
https://ncbi.nlm.nih.gov/pubmed/32286812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c00747
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