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Quantitative Interpretation of Solvent Paramagnetic Relaxation for Probing Protein–Cosolute Interactions
Protein–small cosolute molecule interactions are ubiquitous and known to modulate the solubility, stability, and function of many proteins. Characterization of such transient weak interactions at atomic resolution remains challenging. In this work, we develop a simple and practical NMR method for ex...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7372007/ https://ncbi.nlm.nih.gov/pubmed/32286812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c00747 |
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