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Optimization of Tris/EDTA/Sucrose (TES) periplasmic extraction for the recovery of functional scFv antibodies

Single-chain variable fragments (scFvs) have gained increased attention among researchers in both academic and industrial fields owing to simple production in E. coli. The E. coli periplasm has been the site of choice for the expression of scFv molecules due to its oxidizing milieu facilitating corr...

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Detalhes bibliográficos
Publicado no:AMB Express
Main Authors: Ghamghami, Elham, Abri Aghdam, Marjan, Tohidkia, Mohammad Reza, Ahmadikhah, Asadollah, Khanmohammadi, Morteza, Mehdipour, Tayebeh, Mokhtarzadeh, Ahad, Baradaran, Behzad
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371774/
https://ncbi.nlm.nih.gov/pubmed/32691183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-01063-x
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