Antibody Responses to Immunization With HCV Envelope Glycoproteins as a Baseline for B cell-Based Vaccine Development

BACKGROUND & AIMS: We investigated antibody responses to hepatitis C virus (HCV) antigens E1 and E2 and the relevance of animal models for vaccine development. We compared antibody responses to vaccination with recombinant E1E2 complex in heathy volunteers, non-human primates (NHPs), and mice. M...

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Publicado no:Gastroenterology
Main Authors: Chen, Fang, Nagy, Kenna, Chavez, Deborah, Willis, Shelby, McBride, Ryan, Giang, Erick, Honda, Andrew, Bukh, Jens, Ordoukhanian, Phillip, Zhu, Jiang, Frey, Sharon, Lanford, Robert, Law, Mansun
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371413/
https://ncbi.nlm.nih.gov/pubmed/31809725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.11.282
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