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Identification of Matrine as a Novel Regulator of the CXCR4 Signaling Axis in Tumor Cells

Matrine, a quinolizidine alkaloid, is commonly employed for treating various viral and inflammatory disorders. Here, we have evaluated matrine for its activity on C-X-C chemokine receptor type 4 (CXCR4) and matrix metalloproteinases (MMP-9/2) expression, and its potential to affect tumor metastasis...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Jung, Young Yun, Um, Jae-Young, Narula, Acharan S., Namjoshi, Ojas A., Blough, Bruce E., Kumar, Alan Prem, Ahn, Kwang Seok
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370290/
https://ncbi.nlm.nih.gov/pubmed/32630806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134731
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