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Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model

Oxymatrine (OMT) is a major alkaloid found in radix Sophorae flavescentis extract and has been reported to exhibit various pharmacological activities. We elucidated the detailed molecular mechanism(s) underlying the therapeutic actions of OMT in non-small cell lung cancer (NSCLC) cells and a xenogra...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Jung, Young Yun, Shanmugam, Muthu K., Narula, Acharan S., Kim, Chulwon, Lee, Jong Hyun, Namjoshi, Ojas A., Blough, Bruce E., Sethi, Gautam, Ahn, Kwang Seok
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356594/
https://ncbi.nlm.nih.gov/pubmed/30621055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11010049
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