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Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma

Natural medicinal plants are multi-targeted in nature and their anti-cancer activities are also complex and varied, thus requiring a more systematic analysis of their modes of action. Since the activation of signal transducer and activator of transcription 3 (STAT3) is often deregulated in non-small...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Lee, Jong Hyun, Kim, Chulwon, Lee, Seok-Geun, Sethi, Gautam, Ahn, Kwang Seok
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265752/
https://ncbi.nlm.nih.gov/pubmed/30413072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10110427
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