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Casticin-Induced Inhibition of Cell Growth and Survival Are Mediated through the Dual Modulation of Akt/mTOR Signaling Cascade

The Akt/mTOR signaling cascade is a critical pathway involved in various physiological and pathological conditions, including regulation of cell proliferation, survival, invasion, and angiogenesis. In the present study, we investigated the anti-neoplastic effects of casticin (CTC), identified from t...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Lee, Jong Hyun, Kim, Chulwon, Um, Jae-Young, Sethi, Gautam, Ahn, Kwang Seok
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406334/
https://ncbi.nlm.nih.gov/pubmed/30813295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11020254
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