Evodiamine Mitigates Cellular Growth and Promotes Apoptosis by Targeting the c-Met Pathway in Prostate Cancer Cells

Evodiamine (EVO) is an indoloquinazoline alkaloid that exerts its various anti-oncogenic actions by blocking phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt), mitogen-activated protein kinase (MAPK), c-Met, and nuclear factor kappa B (NF-κB) signaling pathways, thus leading to apoptosis of...

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Publié dans:Molecules
Auteurs principaux: Hwang, Sun Tae, Um, Jae-Young, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Narula, Acharan S., Namjoshi, Ojas A., Blough, Bruce E., Ahn, Kwang Seok
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144730/
https://ncbi.nlm.nih.gov/pubmed/32183146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25061320
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