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Aldosterone Induces DNA Damage and Activation of Nrf2 Mainly in Tubuli of Mouse Kidneys

Hypertensive patients have an increased risk of developing chronic kidney disease (CKD). Many of these patients have increased levels of the blood pressure regulating mineralocorticoid aldosterone. As a protection against aldosterone-induced damage, kidney cells can upregulate key regulators of the...

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Pubblicato in:Int J Mol Sci
Autori principali: Balhorn, Ronja, Hartmann, Christina, Schupp, Nicole
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370281/
https://ncbi.nlm.nih.gov/pubmed/32630085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134679
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