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Oxidative DNA Damage in Kidneys and Heart of Hypertensive Mice Is Prevented by Blocking Angiotensin II and Aldosterone Receptors

INTRODUCTION: Recently, we could show that angiotensin II, the reactive peptide of the blood pressure-regulating renin-angiotensin-aldosterone-system, causes the formation of reactive oxygen species and DNA damage in kidneys and hearts of hypertensive mice. To further investigate on the one hand the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Brand, Susanne, Amann, Kerstin, Mandel, Philipp, Zimnol, Anna, Schupp, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297153/
https://ncbi.nlm.nih.gov/pubmed/25551569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115715
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