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Aldosterone Induces DNA Damage and Activation of Nrf2 Mainly in Tubuli of Mouse Kidneys

Hypertensive patients have an increased risk of developing chronic kidney disease (CKD). Many of these patients have increased levels of the blood pressure regulating mineralocorticoid aldosterone. As a protection against aldosterone-induced damage, kidney cells can upregulate key regulators of the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Balhorn, Ronja, Hartmann, Christina, Schupp, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370281/
https://ncbi.nlm.nih.gov/pubmed/32630085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134679
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