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Aldosterone Induces DNA Damage and Activation of Nrf2 Mainly in Tubuli of Mouse Kidneys

Hypertensive patients have an increased risk of developing chronic kidney disease (CKD). Many of these patients have increased levels of the blood pressure regulating mineralocorticoid aldosterone. As a protection against aldosterone-induced damage, kidney cells can upregulate key regulators of the...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Balhorn, Ronja, Hartmann, Christina, Schupp, Nicole
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370281/
https://ncbi.nlm.nih.gov/pubmed/32630085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134679
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