A Dipeptidyl Peptidase-4 Inhibitor Inhibits Foam Cell Formation of Macrophages in Type 1 Diabetes via Suppression of CD36 and ACAT-1 Expression

Dipeptidyl peptidase-4 (DPP-4) inhibitors have been reported to play a protective role against atherosclerosis in both animal models and patients with type 2 diabetes (T2D). However, since T2D is associated with dyslipidemia, hypertension and insulin resistance, part of which are ameliorated by DPP-...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Terasaki, Michishige, Yashima, Hironori, Mori, Yusaku, Saito, Tomomi, Matsui, Takanori, Hiromura, Munenori, Kushima, Hideki, Osaka, Naoya, Ohara, Makoto, Fukui, Tomoyasu, Hirano, Tsutomu, Yamagishi, Sho-ichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369823/
https://ncbi.nlm.nih.gov/pubmed/32646003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134811
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