AGE-RAGE Axis Stimulates Oxidized LDL Uptake into Macrophages through Cyclin-Dependent Kinase 5-CD36 Pathway via Oxidative Stress Generation

Advanced glycation end products (AGEs) are localized in macrophage-derived foam cells within atherosclerotic lesions, which could be associated with the increased risk of atherosclerotic cardiovascular disease under diabetic conditions. Although foam cell formation of macrophages has been shown to b...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yashima, Hironori, Terasaki, Michishige, Sotokawauchi, Ami, Matsui, Takanori, Mori, Yusaku, Saito, Tomomi, Osaka, Naoya, Kushima, Hideki, Hiromura, Munenori, Ohara, Makoto, Fukui, Tomoyasu, Yamagishi, Sho-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730944/
https://ncbi.nlm.nih.gov/pubmed/33291667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239263
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