AGE-RAGE Axis Stimulates Oxidized LDL Uptake into Macrophages through Cyclin-Dependent Kinase 5-CD36 Pathway via Oxidative Stress Generation

Advanced glycation end products (AGEs) are localized in macrophage-derived foam cells within atherosclerotic lesions, which could be associated with the increased risk of atherosclerotic cardiovascular disease under diabetic conditions. Although foam cell formation of macrophages has been shown to b...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Yashima, Hironori, Terasaki, Michishige, Sotokawauchi, Ami, Matsui, Takanori, Mori, Yusaku, Saito, Tomomi, Osaka, Naoya, Kushima, Hideki, Hiromura, Munenori, Ohara, Makoto, Fukui, Tomoyasu, Yamagishi, Sho-ichi
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730944/
https://ncbi.nlm.nih.gov/pubmed/33291667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239263
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