Combination Therapy with a Sodium-Glucose Cotransporter 2 Inhibitor and a Dipeptidyl Peptidase-4 Inhibitor Additively Suppresses Macrophage Foam Cell Formation and Atherosclerosis in Diabetic Mice

Dipeptidyl peptidase-4 inhibitors (DPP-4is), in addition to their antihyperglycemic roles, have antiatherosclerotic effects. We reported that sodium-glucose cotransporter 2 inhibitors (SGLT2is) suppress atherosclerosis in a glucose-dependent manner in diabetic mice. Here, we investigated the effects...

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Detalhes bibliográficos
Publicado no:Int J Endocrinol
Main Authors: Terasaki, Michishige, Hiromura, Munenori, Mori, Yusaku, Kohashi, Kyoko, Kushima, Hideki, Ohara, Makoto, Watanabe, Takuya, Andersson, Olov, Hirano, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376482/
https://ncbi.nlm.nih.gov/pubmed/28408925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1365209
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