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Route of 41BB/41BBL Costimulation Determines Effector Function of B7-H3-CAR.CD28ζ T Cells
B7-H3 is actively being explored as an immunotherapy target for pediatric patients with solid tumors using monoclonal antibodies or T cells expressing chimeric antigen receptors (CARs). B7-H3-CARs containing a 41BB costimulatory domain are currently favored by several groups based on preclinical stu...
שמור ב:
| הוצא לאור ב: | Mol Ther Oncolytics |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Gene & Cell Therapy
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7369352/ https://ncbi.nlm.nih.gov/pubmed/32728609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.06.018 |
| תגים: |
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