Identification of α-Fetoprotein-Specific T-Cell Receptors for Hepatocellular Carcinoma Immunotherapy

Hepatocellular carcinoma (HCC) is the major form of liver cancer for which there is no effective therapy. Genetic modification with T-cell receptors (TCRs) specific for HCC-associated antigens, such as α-fetoprotein (AFP), can potentially redirect human T cells to specifically recognize and kill HCC...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Zhu, Wei, Peng, Yibing, Wang, Lan, Hong, Yuan, Jiang, Xiaotao, Li, Qi, Liu, Heping, Huang, Lei, Wu, Juan, Celis, Esteban, Merchen, Todd, Kruse, Edward, He, Yukai
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368991/
https://ncbi.nlm.nih.gov/pubmed/29443377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29844
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