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Engineering α-fetoprotein-based gene vaccines to prevent and treat hepatocellular carcinoma: review and future prospects

Activation of a patient’s immune system offers an attractive approach to prevent and treat hepatocellular carcinoma (HCC). However, the antitumor efficacy of current HCC vaccines was weak owing to insufficient immune activation of targeting self/ tumor antigens. We recently found that epitope-optimi...

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Detalhes bibliográficos
Main Authors: He, Yukai, Hong, Yuan, Mizejewski, Gerald J
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151252/
https://ncbi.nlm.nih.gov/pubmed/25041030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.14.46
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