Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions

The difficulty of achieving robust functional expression of insect nicotinic acetylcholine receptors (nAChRs) has hampered our understanding of these important molecular targets of globally deployed neonicotinoid insecticides at a time when concerns have grown regarding the toxicity of this chemotyp...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ihara, Makoto, Furutani, Shogo, Shigetou, Sho, Shimada, Shota, Niki, Kunihiro, Komori, Yuma, Kamiya, Masaki, Koizumi, Wataru, Magara, Leo, Hikida, Mai, Noguchi, Akira, Okuhara, Daiki, Yoshinari, Yuto, Kondo, Shu, Tanimoto, Hiromu, Niwa, Ryusuke, Sattelle, David B., Matsuda, Kazuhiko
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368294/
https://ncbi.nlm.nih.gov/pubmed/32611810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003667117
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