Risk Assessment of the Tropism and Pathogenesis of the Highly Pathogenic Avian Influenza A/H7N9 Virus Using Ex Vivo and In Vitro Cultures of Human Respiratory Tract

BACKGROUND: Highly pathogenic avian influenza (HPAI)-H7N9 virus arising from low pathogenic avian influenza (LPAI)-H7N9 virus with polybasic amino acid substitutions in the hemagglutinin was detected in 2017. METHODS: We compared the tropism, replication competence, and cytokine induction of HPAI-H7...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Chan, Louisa L Y, Hui, Kenrie P Y, Kuok, Denise I T, Bui, Christine H T, Ng, Ka-chun, Mok, Chris K P, Yang, Zi-feng, Guan, Wenda, Poon, Leo L M, Zhong, Nanshan, Peiris, J S Malik, Nicholls, John M, Chan, Michael C W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368241/
https://ncbi.nlm.nih.gov/pubmed/31001638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz165
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