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Loss of polycystins suppresses deciliation via the activation of the centrosomal integrity pathway

The primary cilium is a microtubule-based, antenna-like organelle housing several signaling pathways. It follows a cyclic pattern of assembly and deciliation (disassembly and/or shedding), as cells exit and re-enter the cell cycle, respectively. In general, primary cilia loss leads to kidney cystoge...

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Bibliografske podrobnosti
izdano v:Life Sci Alliance
Main Authors: Gerakopoulos, Vasileios, Ngo, Peter, Tsiokas, Leonidas
Format: Artigo
Jezik:Inglês
Izdano: Life Science Alliance LLC 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368097/
https://ncbi.nlm.nih.gov/pubmed/32651191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000750
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