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SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1
The mechanisms underlying many of the human disease phenotypes associated with ciliary dysfunction and abnormal centrosome amplification have yet to be fully elucidated. Here, we present for the first time that SIRT2, a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase, regulates cilioge...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929098/ https://ncbi.nlm.nih.gov/pubmed/24203696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt556 |
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