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The belated US FDA approval of the adenosine A(2A) receptor antagonist istradefylline for treatment of Parkinson’s disease

After more than two decades of preclinical and clinical studies, on August 27, 2019, the US Food and Drug Administration (FDA) approved the adenosine A(2A) receptor antagonist Nourianz® (istradefylline) developed by Kyowa Hakko Kirin Inc., Japan, as an add-on treatment to levodopa in Parkinson’s dis...

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Dettagli Bibliografici
Pubblicato in:Purinergic Signal
Autori principali: Chen, Jiang-Fan, Cunha, Rodrigo A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367999/
https://ncbi.nlm.nih.gov/pubmed/32236790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-020-09694-2
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