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Do caffeine and more selective adenosine A(2A) receptor antagonists protect against dopaminergic neurodegeneration in Parkinson’s disease?

The adenosine A(2A) receptor is a major target of caffeine, the most widely used psychoactive substance worldwide. Large epidemiological studies have long shown caffeine consumption is a strong inverse predictor of Parkinson’s disease (PD). In this review, we first examine the epidemiology of caffei...

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Detalhes bibliográficos
Publicado no:Parkinsonism Relat Disord
Main Authors: Chen, Jiang-Fan, Schwarzschild, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102090/
https://ncbi.nlm.nih.gov/pubmed/33349580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2020.10.024
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