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Adenosine A(2A) receptor antagonist istradefylline reduces daily OFF time in Parkinson’s disease

BackgroundWe evaluated the efficacy and safety of istradefylline, a selective adenosine A(2A) receptor antagonist administered as adjunctive treatment to levodopa for 12 weeks in a double-blind manner in Parkinson’s disease patients with motor complications in Japan. MethodsA total of 373 subjects w...

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Detalhes bibliográficos
Main Authors: Mizuno, Yoshikuni, Kondo, Tomoyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842830/
https://ncbi.nlm.nih.gov/pubmed/23483627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25418
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