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Ascites-induced compression alters the peritoneal microenvironment and promotes metastatic success in ovarian cancer
The majority of women with recurrent ovarian cancer (OvCa) develop malignant ascites with volumes that can reach > 2 L. The resulting elevation in intraperitoneal pressure (IPP), from normal values of 5 mmHg to as high as 22 mmHg, causes striking changes in the loading environment in the peritone...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7367827/ https://ncbi.nlm.nih.gov/pubmed/32681052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68639-2 |
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