Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis

The noncanonical Wnt ligand Wnt5a is found in high concentrations in ascites of women with ovarian cancer. In this study, we elucidated the role of Wnt5a in ovarian cancer metastasis. Wnt5a promoted ovarian tumor cell adhesion to peritoneal mesothelial cells as well as migration and invasion, leadin...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Asem, Marwa, Young, Allison M., Oyama, Carlysa, De La Zerda, Alejandro Claure, Liu, Yueying, Yang, Jing, Hilliard, Tyvette S., Johnson, Jeffery, Harper, Elizabeth I., Guldner, Ian, Zhang, Siyuan, Page-Mayberry, Toni, Kaliney, William J., Stack, M. Sharon
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8245162/
https://ncbi.nlm.nih.gov/pubmed/31932454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1601
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