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Ascites-induced compression alters the peritoneal microenvironment and promotes metastatic success in ovarian cancer

The majority of women with recurrent ovarian cancer (OvCa) develop malignant ascites with volumes that can reach > 2 L. The resulting elevation in intraperitoneal pressure (IPP), from normal values of 5 mmHg to as high as 22 mmHg, causes striking changes in the loading environment in the peritone...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Asem, Marwa, Young, Allison, Oyama, Carlysa, ClaureDeLaZerda, Alejandro, Liu, Yueying, Ravosa, Matthew. J., Gupta, Vijayalaxmi, Jewell, Andrea, Khabele, Dineo, Stack, M. Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367827/
https://ncbi.nlm.nih.gov/pubmed/32681052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68639-2
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