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Upregulation of microRNA-451 attenuates myocardial I/R injury by suppressing HMGB1

Both MicroRNAs and HMGB1 took part in pathological process of myocardial I/R injury though several signaling pathways. We hypothesized that mircoRNA451 (miR-451), a group of small non-coding RNAs, could improve this injury by inhibiting HMGB1. Male SD rats were randomly distributed into 5 groups and...

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Publicat a:PLoS One
Autors principals: Cao, Jianlei, Da, Yurong, Li, Hang, Peng, Yuanyuan, Hu, Xiaorong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367451/
https://ncbi.nlm.nih.gov/pubmed/32678819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235614
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