Paeonol attenuates inflammation by targeting HMGB1 through upregulating miR-339-5p

Sepsis is a life-threatening disease caused by infection. Inflammation is a key pathogenic process in sepsis. Paeonol, an active ingredient in moutan cortex (a Chinese herb), has many pharmacological activities, such as anti-inflammatory and antitumour actions. Previous studies have indicated that p...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Mei, Liyan, He, Meihong, Zhang, Chaoying, Miao, Jifei, Wen, Quan, Liu, Xia, Xu, Qin, Ye, Sen, Ye, Peng, Huang, Huina, Lin, Junli, Zhou, Xiaojing, Zhao, Kai, Chen, Dongfeng, Zhou, Jianhong, Li, Chun, Li, Hui
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920373/
https://ncbi.nlm.nih.gov/pubmed/31852965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55980-4
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